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Category: Biomedical Engineering

Gleaning Insights from Uber’s Partner Activity Matrix with Genomic Biclustering and Machine Learning

At Uber, machine learning plays a central role in improving user experiences across our apps. Given the scale and scope of our business, we often need to think creatively about how we design these systems. For instance, when developing our partner activity matrix, a new tool for personalizing driver experiences based on aggregate usage trends, we found inspiration in a biomedical technique for visualizing genomes (genomic biclustering). Using biclustering, we can visualize diversity in driver partner patterns by expressing each…

Deletion of a stem cell factor promotes traumatic brain injury recovery in mice — ScienceDaily

UT Southwestern molecular biologists today report the unexpected finding that selectively deleting a stem cell transcription factor in adult mice promotes recovery after traumatic brain injury (TBI). The Centers for Disease Control and Prevention defines TBI as a bump, blow, or jolt to the head that disrupts normal brain function, ranging from mild — brief changes in mental status — to severe, marked by an extended period of unconsciousness or memory loss. In humans, most TBIs are mild and are…

Researchers develop smart, ultra-thin microfibre sensor for real-time healthcare monitoring and diagnosis

A research team led by Professor Lim Chwee Teck (standing) from the Department of Biomedical Engineering at NUS Faculty of Engineering has developed a soft, flexible and stretchable microfibre sensor for real-time healthcare monitoring and diagnosis. The sensor can measure pulse waveform in real-time, and the information can be used to determine one’s heart rate, blood pressure and stiffness in blood vessels. Credit: National University of Singapore A research team from National University of Singapore (NUS) has developed a soft,…

Research team creates powerful system to identify biological threats

The Functional Genomic and Computational Assessment of Threats (Fun GCAT) program challenges research teams to develop new approaches for screening genetic information for evidence of a potential biological threat. Credit: Virginia Tech A team led by investigators from the Biocomplexity Institute of Virginia Tech has been selected through a competitive process to participate in a multimillion dollar program sponsored by the Intelligence Advanced Research Projects Activity (IARPA). The Functional Genomic and Computational Assessment of Threats (Fun GCAT) program challenges research…

Stem cell laboratory in a bag

The mini laboratory is 150 mm long, 120 mm wide and 20 mm high. The screw cap is made using 3D printing. Hydrophilic spots are visible on the upper interior surface of the bag. Credit: Fraunhofer-Gesellschaft Human stem cells are considered a major new hope in the field of medicine. In the future, it is expected that they will make it possible to treat a wide range of ailments such as neurodegenerative diseases. With LabBag, Fraunhofer researchers have developed an…

Dutch design lab blends naturalistic and futuristic

This Sept. 28, 2017 photo provided by the Cooper Hewitt, Smithsonian Design Museum, shows an Installation view of “Joris Laarman Lab: Design in the Digital Age,” in New York. (Matt Flynn/Cooper Hewitt, Smithsonian Design Museum via AP) The first U.S. museum exhibit devoted solely to the experimental and futuristic work of Dutch design studio Joris Laarman Lab is now on view at the Cooper Hewitt Smithsonian Design Museum here. The works—mainly furniture, along with an unusual radiator and a newly…

New methods tackle a perplexing engineering concept

Sreekalyan Patiballa, left, and professor Girish Krishnan have developed a new, award-winning conceptual model to better define the complicated concept of auxetic materials. Credit: L. Brian Stauffer Researchers at the University of Illinois are working to turn a complex materials design problem into an intuitive concept, understandable to engineers from novice to advanced experience levels. The group developed guidelines to help understand materials engineered to become thicker when stretched. This highly useful property, which is not commonly found in nature,…

Smart bandage could promote better, faster healing

Credit: Shutterstock Researchers from the University of Nebraska-Lincoln, Harvard Medical School and MIT have designed a smart bandage that could eventually heal chronic wounds or battlefield injuries with every fiber of its being. The bandage consists of electrically conductive fibers coated in a gel that can be individually loaded with infection-fighting antibiotics, tissue-regenerating growth factors, painkillers or other medications. A microcontroller no larger than a postage stamp, which could be triggered by a smartphone or other wireless device, sends…

Painless microneedles extract fluid for wearable sensors for soldiers, athletes

Sandia National Laboratories materials scientist Ronen Polsky positions a prototype 3-D-printed microneedle holder on the arm of Sandia science writer Mollie Rappe. Rappe participated in a clinical trial to see the best length of needle to extract the interstitial fluid on the path to track the physiological condition of soldiers. Credit: Randy Montoya The lab is calm and quiet, clean and well organized; boxes of tiny needles and sample tubes are neatly stacked above a pristine paper-covered countertop. This is…

Genes which determine animal complexity, or what makes humans so much more complex than a fruit fly or a sea urchin, have been identified for the first time — ScienceDaily

Genes which determine animal complexity — or what makes humans so much more complex than a fruit fly or a sea urchin — have been identified for the first time. The secret mechanism for how a cell in one animal can be significantly more complex than a similar cell in another animal appears to be due to proteins and their ability to control ‘events’ in a cell’s nucleus. The research, by biochemist Dr Colin Sharpe and colleagues in the University…